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KMID : 1161220210640120602
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Clinical and Experimental Pediatrics
2021 Volume.64 No. 12 p.602 ~ p.607
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Recommendation for use of diphtheria and tetanus toxoids and acellular pertussis, inactivated poliovirus, Haemophilus influenzae type b conjugate, and hepatitis B vaccine in infants
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Cho Hye-Kyung
Park Su-Eun
Kim Yae-Jean
Jo Dae-Sun
Kim Yun-Kyung
Eun Byung-Wook
Lee Taek-Jin
Lee Jin-A
Lee Hyun-Ju
Kim Ki-Hwan
Cho Eun-Young
Ahn Jong-Gyun
Choi Eun-Hwa
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Abstract
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In April 2020, the Ministry of Food and Drug Safety licensed a hexavalent combined diphtheria and tetanus toxoids and acellular pertussis (DTaP), inactivated poliovirus (IPV), Haemophilus influenzae type b (Hib) conjugated to tetanus protein, and hepatitis B (HepB) (recombinant DNA) vaccine, DTa-PIPV-Hib-HepB (Hexaxim, Sanofi Pasteur), for use as a 3-dose primary series in infants aged 2, 4, and 6 months. The DTaP-IPV-Hib-HepB vaccine is highly immunogenic and safe and provides a long-term immune response based on studies performed in a variety of settings in many countries, including Korea. This report summarizes the Committee on Infectious Diseases of the Korean Pediatric Society guidelines for the use of this newly introduced hexavalent combination vaccine.
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KEYWORD
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Vaccines, Combined, Diphtheria-tetanus-acellular pertussis-inactivate, Infant
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